Difference between revisions of "Genetic Evaluation"

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=[[Expected Progeny Difference]]=
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Predictions of genetic merit for breeding animals is one of the oldest technologies available to mankind.  Identifying animals for [[Selection and Mating | selection and mating]] has evolved from visual appraisal to sophisticated analytical models to predict [[Glossary#A | additive genetic]] merit of animals.  In North America, the standard for identifying genetic merit of breeding animals is [[Expected Progeny Difference | expected progeny differences (EPDs)]].
==Basic Models==
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With very few ''ad hoc'' exceptions, EPDs are produced for North American beef cattle using models based on [[Best Linear Unbiased Prediction]]
===BLUP===
 
===[[Single-step Genomic BLUP]]===
 
  
===[[Single-step Hybrid Marker Effects Models]]===
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While not all [[Economically Relevant Traits | economically relevant traits]] in all situations and in all North American breed registries have EPDs available, the number of [[EPD Traits | traits and trait components]] that have EPDs has increased dramatically.
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Nearly all the major North American beef cattle breed organizations have migrated to weekly updates to their EPDs, eliminating the need for [[Interim EPDs | interim EPDs]].
  
==Interim Calculations==
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Most of the improvements in the technologies used to produce EPDs has been motivated by an opportunity to increase [[Accuracy | accuracy of prediction]]. For example, the advent of [[Genotyping | genomic information]] to enhance the [[Accuracy | accuracy]] of prediction has resulted in EPDs for most traits being produced using either [[Single-step Genomic BLUP]] or [[Single-step Hybrid Marker Effects Models]]. 
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In commercial cattle production, EPDs for [[Economically Relevant Traits | economically relevant traits]] should be combined with appropriate selection tools such as [[Selection Index | selection indices]] to make optimal genetic progress.  It must be remembered that EPDs are just parameters to make genetic progress and manage certain genetic risks.
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In some special situations in seed stock production breeders may need to make selection decisions using EPDs that are not [[Economically relevant Traits | economically relevant traits]] in commercial settings in order to enhance the marketability of their breed or breeding animals. For example, if a breed has a perceived defect that is limiting that breed organizations' members from expanding their market for selling germplasm, then selection to improve that characteristic should be included in the seed stock breeder's [[Breeding Objectives | breeding objectives]].
  
 
=Bias=  
 
=Bias=  

Revision as of 18:47, 1 March 2019

Predictions of genetic merit for breeding animals is one of the oldest technologies available to mankind. Identifying animals for selection and mating has evolved from visual appraisal to sophisticated analytical models to predict additive genetic merit of animals. In North America, the standard for identifying genetic merit of breeding animals is expected progeny differences (EPDs). With very few ad hoc exceptions, EPDs are produced for North American beef cattle using models based on Best Linear Unbiased Prediction.

While not all economically relevant traits in all situations and in all North American breed registries have EPDs available, the number of traits and trait components that have EPDs has increased dramatically. Nearly all the major North American beef cattle breed organizations have migrated to weekly updates to their EPDs, eliminating the need for interim EPDs.

Most of the improvements in the technologies used to produce EPDs has been motivated by an opportunity to increase accuracy of prediction. For example, the advent of genomic information to enhance the accuracy of prediction has resulted in EPDs for most traits being produced using either Single-step Genomic BLUP or Single-step Hybrid Marker Effects Models.

In commercial cattle production, EPDs for economically relevant traits should be combined with appropriate selection tools such as selection indices to make optimal genetic progress. It must be remembered that EPDs are just parameters to make genetic progress and manage certain genetic risks.

In some special situations in seed stock production breeders may need to make selection decisions using EPDs that are not economically relevant traits in commercial settings in order to enhance the marketability of their breed or breeding animals. For example, if a breed has a perceived defect that is limiting that breed organizations' members from expanding their market for selling germplasm, then selection to improve that characteristic should be included in the seed stock breeder's breeding objectives.

Bias

(in)complete reporting / contemporary groups / preferential treatment (Suggested writer: Bob Weaber

Accuracy (Suggested writer: Matt Spangler)

meaning of accuracy

what impacts accuracy

different definitions of accuracy (true, BIF, reliability)

Variance components (Suggested writer: Steve Kachman)

Impact on EPD, accuracy, genetic gain (Suggested writer: Steve Kachman)

Heterogeneous variance

Connectivity (Suggested writer: Ron Lewis)

Measures of (Suggested writer: Ron Lewis)

==Impact on GE== (Suggested Writer: Ron Lewis)

Current GE

How each breed (organization) is modeling each trait (Suggested writers: Steve Miller, Lauren Hyde, AHA)